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Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis

BACKGROUND: Toll-like receptor 4 (TLR4) is widely recognized as an essential element in the triggering of innate immunity, binding pathogen-associated molecules such as Lipopolysaccharide (LPS), and in initiating a cascade of pro-inflammatory events. Evidence for TLR4 expression in non-immune cells,...

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Detalles Bibliográficos
Autores principales:	Garay-Malpartida, Humberto M, Mourão, Roberta F, Mantovani, Marluce, Santos, Icaro A, Sogayar, Mari C, Goldberg, Anna C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060152/ https://www.ncbi.nlm.nih.gov/pubmed/21356084 http://dx.doi.org/10.1186/1471-2172-12-18

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