Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

Influenza virus sialidase has an essential role in the virus' life cycle. Two distinct groups of influenza A virus sialidases have been established, that differ in the flexibility of the '150-loop', providing a more open active site in the apo form of the group-1 compared to group-2 e...

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Detalles Bibliográficos
Autores principales: Rudrawar, Santosh, Dyason, Jeffrey C., Rameix-Welti, Marie-Anne, Rose, Faith J., Kerry, Philip S., Russell, Rupert J. M., van der Werf, Sylvie, Thomson, Robin J., Naffakh, Nadia, von Itzstein, Mark
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060605/
https://www.ncbi.nlm.nih.gov/pubmed/21081911
http://dx.doi.org/10.1038/ncomms1114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060605/
https://www.ncbi.nlm.nih.gov/pubmed/21081911
http://dx.doi.org/10.1038/ncomms1114

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