Cargando…
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase
Influenza virus sialidase has an essential role in the virus' life cycle. Two distinct groups of influenza A virus sialidases have been established, that differ in the flexibility of the '150-loop', providing a more open active site in the apo form of the group-1 compared to group-2 e...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060605/ https://www.ncbi.nlm.nih.gov/pubmed/21081911 http://dx.doi.org/10.1038/ncomms1114 |