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A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain

The discovery of α-synuclein (αS) mutations has made a major contribution to the understanding of the pathogenesis of α-synucleinopathies such as Parkinson's disease and dementia with Lewy bodies (DLB). In contrast, less attention has been paid to β-synuclein (βS) mutations. In this paper, we s...

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Detalles Bibliográficos
Autores principales: Fujita, Masayo, Sugama, Shuei, Sekiyama, Kazunari, Sekigawa, Akio, Tsukui, Tohru, Nakai, Masaaki, Waragai, Masaaki, Takenouchi, Takato, Takamatsu, Yoshiki, Wei, Jianshe, Rockenstein, Edward, LaSpada, Albert R., Masliah, Eliezer, Inoue, Satoshi, Hashimoto, Makoto
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060620/
https://www.ncbi.nlm.nih.gov/pubmed/21045828
http://dx.doi.org/10.1038/ncomms1101