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Sublancin is not a lantibiotic but an S-linked glycopeptide
Sublancin is shown to be an S-linked glycopeptide containing a glucose attached to a Cys residue, establishing a new post-translational modification. The activity of the S-glycosyl transferase was reconstituted in vitro and the enzyme is shown to have relaxed substrate specificity allowing the prepa...
Autores principales: | Oman, Trent J., Boettcher, John M., Wang, Huan, Okalibe, Xenia N., van der Donk, Wilfred A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060661/ https://www.ncbi.nlm.nih.gov/pubmed/21196935 http://dx.doi.org/10.1038/nchembio.509 |
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