Astroglial Inhibition of NF-κB Does Not Ameliorate Disease Onset and Progression in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)

Motor neuron death in amyotrophic lateral sclerosis (ALS) is considered a “non-cell autonomous” process, with astrocytes playing a critical role in disease progression. Glial cells are activated early in transgenic mice expressing mutant SOD1, suggesting that neuroinflammation has a relevant role in...

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Detalles Bibliográficos
Autores principales: Crosio, Claudia, Valle, Cristiana, Casciati, Arianna, Iaccarino, Ciro, Carrì, Maria Teresa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060799/
https://www.ncbi.nlm.nih.gov/pubmed/21445241
http://dx.doi.org/10.1371/journal.pone.0017187

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