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Prion Protein Polymorphisms Affect Chronic Wasting Disease Progression

Analysis of the PRNP gene in cervids naturally infected with chronic wasting disease (CWD) suggested that PRNP polymorphisms affect the susceptibility of deer to infection. To test this effect, we orally inoculated 12 white-tailed deer with CWD agent. Three different PRNP alleles, wild-type (wt; glu...

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Detalles Bibliográficos
Autores principales: Johnson, Chad J., Herbst, Allen, Duque-Velasquez, Camilo, Vanderloo, Joshua P., Bochsler, Phil, Chappell, Rick, McKenzie, Debbie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060816/
https://www.ncbi.nlm.nih.gov/pubmed/21445256
http://dx.doi.org/10.1371/journal.pone.0017450