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Assessing Matched Normal and Tumor Pairs in Next-Generation Sequencing Studies

Next generation sequencing technology has revolutionized the study of cancers. Through matched normal-tumor pairs, it is now possible to identify genome-wide germline and somatic mutations. The generation and analysis of the data requires rigorous quality checks and filtering, and the current analyt...

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Detalles Bibliográficos
Autores principales:	Goh, Liang, Chen, Geng Bo, Cutcutache, Ioana, Low, Benjamin, Teh, Bin Tean, Rozen, Steve, Tan, Patrick
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060821/ https://www.ncbi.nlm.nih.gov/pubmed/21445261 http://dx.doi.org/10.1371/journal.pone.0017810

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