A Common Polymorphism in the Promoter Region of the TNFSF4 Gene Is Associated with Lower Allele-Specific Expression and Risk of Myocardial Infarction

BACKGROUND: The TNFSF4/TNFRSF4 system, along with several other receptor-ligand pairs, is involved in the recruitment and activation of T-cells and is therefore tentatively implicated in atherosclerosis and acute coronary syndromes. We have previously shown that genetic variants in TNFSF4 are associ...

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Detalles Bibliográficos
Autores principales: Ria, Massimiliano, Lagercrantz, Jacob, Samnegård, Ann, Boquist, Susanna, Hamsten, Anders, Eriksson, Per
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060868/
https://www.ncbi.nlm.nih.gov/pubmed/21445270
http://dx.doi.org/10.1371/journal.pone.0017652

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