Histone Demethylase JMJD2B Functions as a Co-Factor of Estrogen Receptor in Breast Cancer Proliferation and Mammary Gland Development

Estrogen is a key regulator of normal function of female reproductive system and plays a pivotal role in the development and progression of breast cancer. Here, we demonstrate that JMJD2B (also known as KDM4B) constitutes a key component of the estrogen signaling pathway. JMJD2B is expressed in a hi...

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Detalles Bibliográficos
Autores principales: Kawazu, Masahito, Saso, Kayoko, Tong, Kit I., McQuire, Tracy, Goto, Kouichiro, Son, Dong-Ok, Wakeham, Andrew, Miyagishi, Makoto, Mak, Tak W., Okada, Hitoshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060874/
https://www.ncbi.nlm.nih.gov/pubmed/21445275
http://dx.doi.org/10.1371/journal.pone.0017830

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