Cargando…

Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial

OBJECTIVE: We examined the effects of an aerobic exercise intervention on adiposity outcomes that may be involved in the association between physical activity and breast cancer risk. DESIGN: This study was a two-centre, two-armed, randomized controlled trial. The 1-year-long exercise intervention in...

Descripción completa

Detalles Bibliográficos
Autores principales: Friedenreich, C M, Woolcott, C G, McTiernan, A, Terry, T, Brant, R, Ballard-Barbash, R, Irwin, M L, Jones, C A, Boyd, N F, Yaffe, M J, Campbell, K L, McNeely, M L, Karvinen, K H, Courneya, K S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061001/
https://www.ncbi.nlm.nih.gov/pubmed/20820172
http://dx.doi.org/10.1038/ijo.2010.147
_version_ 1782200567719788544
author Friedenreich, C M
Woolcott, C G
McTiernan, A
Terry, T
Brant, R
Ballard-Barbash, R
Irwin, M L
Jones, C A
Boyd, N F
Yaffe, M J
Campbell, K L
McNeely, M L
Karvinen, K H
Courneya, K S
author_facet Friedenreich, C M
Woolcott, C G
McTiernan, A
Terry, T
Brant, R
Ballard-Barbash, R
Irwin, M L
Jones, C A
Boyd, N F
Yaffe, M J
Campbell, K L
McNeely, M L
Karvinen, K H
Courneya, K S
author_sort Friedenreich, C M
collection PubMed
description OBJECTIVE: We examined the effects of an aerobic exercise intervention on adiposity outcomes that may be involved in the association between physical activity and breast cancer risk. DESIGN: This study was a two-centre, two-armed, randomized controlled trial. The 1-year-long exercise intervention included 45 min of moderate-to-vigorous aerobic exercise five times per week, with at least three of the sessions being facility based. The control group was asked not to change their activity and both groups were asked not to change their diet. SUBJECTS: A total of 320 postmenopausal, sedentary, normal weight-to-obese women aged 50–74 years who were cancer-free, nondiabetic and nonhormone replacement therapy users were included in this study. MEASUREMENTS: Anthropometric measurements of height, weight and waist and hip circumferences; dual energy X-ray absorptiometry measurements of total body fat; and computerized tomography measurements of abdominal adiposity were carried out. RESULTS: Women in the exercise group exercised a mean of 3.6 days (s.d.=1.3) per week and 178.5 min (s.d.=76.1) per week. Changes in all measures of adiposity favored exercisers relative to controls (P<0.001). The mean difference between groups was: −1.8 kg for body weight; −2.0 kg for total body fat; −14.9 cm(2) for intra-abdominal fat area; and −24.1 cm(2) for subcutaneous abdominal fat area. A linear trend of greater body fat loss with increasing volume of exercise was also observed. CONCLUSION: A 1-year aerobic exercise program consistent with current public health guidelines resulted in reduced adiposity levels in previously sedentary postmenopausal women at higher risk of breast cancer.
format Text
id pubmed-3061001
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-30610012011-03-30 Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial Friedenreich, C M Woolcott, C G McTiernan, A Terry, T Brant, R Ballard-Barbash, R Irwin, M L Jones, C A Boyd, N F Yaffe, M J Campbell, K L McNeely, M L Karvinen, K H Courneya, K S Int J Obes (Lond) Original Article OBJECTIVE: We examined the effects of an aerobic exercise intervention on adiposity outcomes that may be involved in the association between physical activity and breast cancer risk. DESIGN: This study was a two-centre, two-armed, randomized controlled trial. The 1-year-long exercise intervention included 45 min of moderate-to-vigorous aerobic exercise five times per week, with at least three of the sessions being facility based. The control group was asked not to change their activity and both groups were asked not to change their diet. SUBJECTS: A total of 320 postmenopausal, sedentary, normal weight-to-obese women aged 50–74 years who were cancer-free, nondiabetic and nonhormone replacement therapy users were included in this study. MEASUREMENTS: Anthropometric measurements of height, weight and waist and hip circumferences; dual energy X-ray absorptiometry measurements of total body fat; and computerized tomography measurements of abdominal adiposity were carried out. RESULTS: Women in the exercise group exercised a mean of 3.6 days (s.d.=1.3) per week and 178.5 min (s.d.=76.1) per week. Changes in all measures of adiposity favored exercisers relative to controls (P<0.001). The mean difference between groups was: −1.8 kg for body weight; −2.0 kg for total body fat; −14.9 cm(2) for intra-abdominal fat area; and −24.1 cm(2) for subcutaneous abdominal fat area. A linear trend of greater body fat loss with increasing volume of exercise was also observed. CONCLUSION: A 1-year aerobic exercise program consistent with current public health guidelines resulted in reduced adiposity levels in previously sedentary postmenopausal women at higher risk of breast cancer. Nature Publishing Group 2011-03 2010-09-07 /pmc/articles/PMC3061001/ /pubmed/20820172 http://dx.doi.org/10.1038/ijo.2010.147 Text en Copyright © 2011 Macmillan Publishers Limited http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Original Article
Friedenreich, C M
Woolcott, C G
McTiernan, A
Terry, T
Brant, R
Ballard-Barbash, R
Irwin, M L
Jones, C A
Boyd, N F
Yaffe, M J
Campbell, K L
McNeely, M L
Karvinen, K H
Courneya, K S
Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial
title Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial
title_full Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial
title_fullStr Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial
title_full_unstemmed Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial
title_short Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial
title_sort adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061001/
https://www.ncbi.nlm.nih.gov/pubmed/20820172
http://dx.doi.org/10.1038/ijo.2010.147
work_keys_str_mv AT friedenreichcm adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT woolcottcg adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT mctiernana adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT terryt adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT brantr adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT ballardbarbashr adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT irwinml adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT jonesca adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT boydnf adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT yaffemj adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT campbellkl adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT mcneelyml adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT karvinenkh adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial
AT courneyaks adipositychangesaftera1yearaerobicexerciseinterventionamongpostmenopausalwomenarandomizedcontrolledtrial