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The latch modulates nucleotide and DNA binding to the helicase-like domain of Thermotoga maritima reverse gyrase and is required for positive DNA supercoiling

Reverse gyrase is the only topoisomerase that can introduce positive supercoils into DNA in an ATP-dependent process. It has a modular structure and harnesses a helicase-like domain to support a topoisomerase activity, thereby creating the unique function of positive DNA supercoiling. The isolated t...

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Detalles Bibliográficos
Autores principales:	Ganguly, Agneyo, del Toro Duany, Yoandris, Rudolph, Markus G., Klostermeier, Dagmar
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061058/ https://www.ncbi.nlm.nih.gov/pubmed/21051354 http://dx.doi.org/10.1093/nar/gkq1048

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