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Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats

R-loops have been described at immunoglobulin class switch sequences, prokaryotic and mitochondrial replication origins, and disease-associated (CAG)n and (GAA)n trinucleotide repeats. The determinants of trinucleotide R-loop formation are unclear. Trinucleotide repeat expansions cause diseases incl...

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Detalles Bibliográficos
Autores principales: Reddy, Kaalak, Tam, Mandy, Bowater, Richard P., Barber, Miriam, Tomlinson, Matthew, Nichol Edamura, Kerrie, Wang, Yuh-Hwa, Pearson, Christopher E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061079/
https://www.ncbi.nlm.nih.gov/pubmed/21051337
http://dx.doi.org/10.1093/nar/gkq935

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