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Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats
R-loops have been described at immunoglobulin class switch sequences, prokaryotic and mitochondrial replication origins, and disease-associated (CAG)n and (GAA)n trinucleotide repeats. The determinants of trinucleotide R-loop formation are unclear. Trinucleotide repeat expansions cause diseases incl...
Autores principales: | Reddy, Kaalak, Tam, Mandy, Bowater, Richard P., Barber, Miriam, Tomlinson, Matthew, Nichol Edamura, Kerrie, Wang, Yuh-Hwa, Pearson, Christopher E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061079/ https://www.ncbi.nlm.nih.gov/pubmed/21051337 http://dx.doi.org/10.1093/nar/gkq935 |
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