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Chemotherapy-resistant osteosarcoma is highly susceptible to IL-15-activated allogeneic and autologous NK cells
High-grade osteosarcoma occurs predominantly in adolescents and young adults and has an overall survival rate of about 60%, despite chemotherapy and surgery. Therefore, novel treatment modalities are needed to prevent or treat recurrent disease. Natural killer (NK) cells are lymphocytes with cytotox...
Autores principales: | Buddingh, Emilie P., Schilham, Marco W., Ruslan, S. Eriaty N., Berghuis, Dagmar, Szuhai, Karoly, Suurmond, Jolien, Taminiau, Antonie H. M., Gelderblom, Hans, Egeler, R. Maarten, Serra, Massimo, Hogendoorn, Pancras C. W., Lankester, Arjan C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061210/ https://www.ncbi.nlm.nih.gov/pubmed/21240486 http://dx.doi.org/10.1007/s00262-010-0965-3 |
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