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The Embryonic Stem Cell Test as Tool to Assess Structure-Dependent Teratogenicity: The Case of Valproic Acid
Teratogenicity can be predicted in vitro using the embryonic stem cell test (EST). The EST, which is based on the morphometric measurement of cardiomyocyte differentiation and cytotoxicity parameters, represents a scientifically validated method for the detection and classification of chemicals acco...
Autores principales: | Riebeling, Christian, Pirow, Ralph, Becker, Klaus, Buesen, Roland, Eikel, Daniel, Kaltenhäuser, Johanna, Meyer, Frauke, Nau, Heinz, Slawik, Birgitta, Visan, Anke, Volland, Jutta, Spielmann, Horst, Luch, Andreas, Seiler, Andrea |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061479/ https://www.ncbi.nlm.nih.gov/pubmed/21227905 http://dx.doi.org/10.1093/toxsci/kfr001 |
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