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Helicobacter pylori CagA Disrupts Epithelial Patterning by Activating Myosin Light Chain

Helicobacter pylori infection is a leading cause of ulcers and gastric cancer. We show that expression of the H. pylori virulence factor CagA in a model Drosophila melanogaster epithelium induces morphological disruptions including ectopic furrowing. We find that CagA alters the distribution and inc...

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Detalles Bibliográficos
Autores principales: Muyskens, Jonathan B., Guillemin, Karen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061873/
https://www.ncbi.nlm.nih.gov/pubmed/21445303
http://dx.doi.org/10.1371/journal.pone.0017856