Cargando…
Sensitivity of temporal heart rate variability in Poincaré plot to changes in parasympathetic nervous system activity
BACKGROUND: A novel descriptor (Complex Correlation Measure (CCM)) for measuring the variability in the temporal structure of Poincaré plot has been developed to characterize or distinguish between Poincaré plots with similar shapes. METHODS: This study was designed to assess the changes in temporal...
Autores principales: | , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061954/ https://www.ncbi.nlm.nih.gov/pubmed/21366929 http://dx.doi.org/10.1186/1475-925X-10-17 |
_version_ | 1782200676717166592 |
---|---|
author | Karmakar, Chandan K Khandoker, Ahsan H Voss, Andreas Palaniswami, Marimuthu |
author_facet | Karmakar, Chandan K Khandoker, Ahsan H Voss, Andreas Palaniswami, Marimuthu |
author_sort | Karmakar, Chandan K |
collection | PubMed |
description | BACKGROUND: A novel descriptor (Complex Correlation Measure (CCM)) for measuring the variability in the temporal structure of Poincaré plot has been developed to characterize or distinguish between Poincaré plots with similar shapes. METHODS: This study was designed to assess the changes in temporal structure of the Poincaré plot using CCM during atropine infusion, 70° head-up tilt and scopolamine administration in healthy human subjects. CCM quantifies the point-to-point variation of the signal rather than gross description of the Poincaré plot. The physiological relevance of CCM was demonstrated by comparing the changes in CCM values with autonomic perturbation during all phases of the experiment. The sensitivities of short term variability (SD1), long term variability (SD2) and variability in temporal structure (CCM) were analyzed by changing the temporal structure by shuffling the sequences of points of the Poincaré plot. Surrogate analysis was used to show CCM as a measure of changes in temporal structure rather than random noise and sensitivity of CCM with changes in parasympathetic activity. RESULTS: CCM was found to be most sensitive to changes in temporal structure of the Poincaré plot as compared to SD1 and SD2. The values of all descriptors decreased with decrease in parasympathetic activity during atropine infusion and 70° head-up tilt phase. In contrast, values of all descriptors increased with increase in parasympathetic activity during scopolamine administration. CONCLUSIONS: The concordant reduction and enhancement in CCM values with parasympathetic activity indicates that the temporal variability of Poincaré plot is modulated by the parasympathetic activity which correlates with changes in CCM values. CCM is more sensitive than SD1 and SD2 to changes of parasympathetic activity. |
format | Text |
id | pubmed-3061954 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-30619542011-03-31 Sensitivity of temporal heart rate variability in Poincaré plot to changes in parasympathetic nervous system activity Karmakar, Chandan K Khandoker, Ahsan H Voss, Andreas Palaniswami, Marimuthu Biomed Eng Online Research BACKGROUND: A novel descriptor (Complex Correlation Measure (CCM)) for measuring the variability in the temporal structure of Poincaré plot has been developed to characterize or distinguish between Poincaré plots with similar shapes. METHODS: This study was designed to assess the changes in temporal structure of the Poincaré plot using CCM during atropine infusion, 70° head-up tilt and scopolamine administration in healthy human subjects. CCM quantifies the point-to-point variation of the signal rather than gross description of the Poincaré plot. The physiological relevance of CCM was demonstrated by comparing the changes in CCM values with autonomic perturbation during all phases of the experiment. The sensitivities of short term variability (SD1), long term variability (SD2) and variability in temporal structure (CCM) were analyzed by changing the temporal structure by shuffling the sequences of points of the Poincaré plot. Surrogate analysis was used to show CCM as a measure of changes in temporal structure rather than random noise and sensitivity of CCM with changes in parasympathetic activity. RESULTS: CCM was found to be most sensitive to changes in temporal structure of the Poincaré plot as compared to SD1 and SD2. The values of all descriptors decreased with decrease in parasympathetic activity during atropine infusion and 70° head-up tilt phase. In contrast, values of all descriptors increased with increase in parasympathetic activity during scopolamine administration. CONCLUSIONS: The concordant reduction and enhancement in CCM values with parasympathetic activity indicates that the temporal variability of Poincaré plot is modulated by the parasympathetic activity which correlates with changes in CCM values. CCM is more sensitive than SD1 and SD2 to changes of parasympathetic activity. BioMed Central 2011-03-03 /pmc/articles/PMC3061954/ /pubmed/21366929 http://dx.doi.org/10.1186/1475-925X-10-17 Text en Copyright ©2011 Karmakar et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Karmakar, Chandan K Khandoker, Ahsan H Voss, Andreas Palaniswami, Marimuthu Sensitivity of temporal heart rate variability in Poincaré plot to changes in parasympathetic nervous system activity |
title | Sensitivity of temporal heart rate variability in Poincaré plot to changes in parasympathetic nervous system activity |
title_full | Sensitivity of temporal heart rate variability in Poincaré plot to changes in parasympathetic nervous system activity |
title_fullStr | Sensitivity of temporal heart rate variability in Poincaré plot to changes in parasympathetic nervous system activity |
title_full_unstemmed | Sensitivity of temporal heart rate variability in Poincaré plot to changes in parasympathetic nervous system activity |
title_short | Sensitivity of temporal heart rate variability in Poincaré plot to changes in parasympathetic nervous system activity |
title_sort | sensitivity of temporal heart rate variability in poincaré plot to changes in parasympathetic nervous system activity |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061954/ https://www.ncbi.nlm.nih.gov/pubmed/21366929 http://dx.doi.org/10.1186/1475-925X-10-17 |
work_keys_str_mv | AT karmakarchandank sensitivityoftemporalheartratevariabilityinpoincareplottochangesinparasympatheticnervoussystemactivity AT khandokerahsanh sensitivityoftemporalheartratevariabilityinpoincareplottochangesinparasympatheticnervoussystemactivity AT vossandreas sensitivityoftemporalheartratevariabilityinpoincareplottochangesinparasympatheticnervoussystemactivity AT palaniswamimarimuthu sensitivityoftemporalheartratevariabilityinpoincareplottochangesinparasympatheticnervoussystemactivity |