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The host genomic environment of the provirus determines the abundance of HTLV-1–infected T-cell clones

Human T-lymphotropic virus type 1 (HTLV-1) persists by driving clonal proliferation of infected T lymphocytes. A high proviral load predisposes to HTLV-1–associated diseases. Yet the reasons for the variation within and between persons in the abundance of HTLV-1–infected clones remain unknown. We de...

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Detalles Bibliográficos
Autores principales:	Gillet, Nicolas A., Malani, Nirav, Melamed, Anat, Gormley, Niall, Carter, Richard, Bentley, David, Berry, Charles, Bushman, Frederic D., Taylor, Graham P., Bangham, Charles R. M.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2011
Materias:	Immunobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062313/ https://www.ncbi.nlm.nih.gov/pubmed/21228324 http://dx.doi.org/10.1182/blood-2010-10-312926

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