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Mutations in Complement Regulatory Proteins Predispose to Preeclampsia: A Genetic Analysis of the PROMISSE Cohort
BACKGROUND: Pregnancy in women with systemic lupus erythematosus (SLE) or antiphospholipid antibodies (APL Ab)—autoimmune conditions characterized by complement-mediated injury—is associated with increased risk of preeclampsia and miscarriage. Our previous studies in mice indicate that complement ac...
Autores principales: | Salmon, Jane E., Heuser, Cara, Triebwasser, Michael, Liszewski, M. Kathryn, Kavanagh, David, Roumenina, Lubka, Branch, D. Ware, Goodship, Tim, Fremeaux-Bacchi, Veronique, Atkinson, John P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062534/ https://www.ncbi.nlm.nih.gov/pubmed/21445332 http://dx.doi.org/10.1371/journal.pmed.1001013 |
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