Increased Incidence of Choroid Plexus Carcinoma Due to the Germline TP53 R337H Mutation in Southern Brazil

BACKGROUND: Choroid plexus carcinomas (CPC) are rare tumors predominantly found in children. Given the high frequency of the germline R337H mutation in the TP53 gene in southern Brazil, we have evaluated the frequency of the R337H mutation in families with CPC in children. METHODOLOGY/PRINCIPAL FIND...

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Detalles Bibliográficos
Autores principales: Custodio, Gislaine, Taques, Guilherme R., Figueiredo, Bonald C., Gugelmin, Elizabeth S., Oliveira Figueiredo, Mirna M., Watanabe, Flora, Pontarolo, Roberto, Lalli, Enzo, Torres, Luiz Fernando Bleggi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062554/
https://www.ncbi.nlm.nih.gov/pubmed/21445348
http://dx.doi.org/10.1371/journal.pone.0018015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062554/
https://www.ncbi.nlm.nih.gov/pubmed/21445348
http://dx.doi.org/10.1371/journal.pone.0018015

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