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Visualization of Spatiotemporal Energy Dynamics of Hippocampal Neurons by Mass Spectrometry during a Kainate-Induced Seizure

We report the use of matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry combined with capillary electrophoresis (CE) mass spectrometry to visualize energy metabolism in the mouse hippocampus by imaging energy-related metabolites. We show the distribution patterns of ATP, A...

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Detalles Bibliográficos
Autores principales: Sugiura, Yuki, Taguchi, Ryo, Setou, Mitsutoshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062556/
https://www.ncbi.nlm.nih.gov/pubmed/21445350
http://dx.doi.org/10.1371/journal.pone.0017952