The Ras Antagonist, Farnesylthiosalicylic Acid (FTS), Decreases Fibrosis and Improves Muscle Strength in dy(2J)/dy(2J) Mouse Model of Muscular Dystrophy

The Ras superfamily of guanosine-triphosphate (GTP)-binding proteins regulates a diverse spectrum of intracellular processes involved in inflammation and fibrosis. Farnesythiosalicylic acid (FTS) is a unique and potent Ras inhibitor which decreased inflammation and fibrosis in experimentally induced...

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Detalles Bibliográficos
Autores principales: Nevo, Yoram, Aga-Mizrachi, Shlomit, Elmakayes, Edva, Yanay, Nurit, Ettinger, Keren, Elbaz, Moran, Brunschwig, Zivia, Dadush, Oshrat, Elad-Sfadia, Galit, Haklai, Roni, Kloog, Yoel, Chapman, Joab, Reif, Shimon
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062565/
https://www.ncbi.nlm.nih.gov/pubmed/21445359
http://dx.doi.org/10.1371/journal.pone.0018049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062565/
https://www.ncbi.nlm.nih.gov/pubmed/21445359
http://dx.doi.org/10.1371/journal.pone.0018049

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