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The Ras Antagonist, Farnesylthiosalicylic Acid (FTS), Decreases Fibrosis and Improves Muscle Strength in dy(2J)/dy(2J) Mouse Model of Muscular Dystrophy
The Ras superfamily of guanosine-triphosphate (GTP)-binding proteins regulates a diverse spectrum of intracellular processes involved in inflammation and fibrosis. Farnesythiosalicylic acid (FTS) is a unique and potent Ras inhibitor which decreased inflammation and fibrosis in experimentally induced...
Autores principales: | Nevo, Yoram, Aga-Mizrachi, Shlomit, Elmakayes, Edva, Yanay, Nurit, Ettinger, Keren, Elbaz, Moran, Brunschwig, Zivia, Dadush, Oshrat, Elad-Sfadia, Galit, Haklai, Roni, Kloog, Yoel, Chapman, Joab, Reif, Shimon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062565/ https://www.ncbi.nlm.nih.gov/pubmed/21445359 http://dx.doi.org/10.1371/journal.pone.0018049 |
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