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Why were "starvation diets" promoted for diabetes in the pre-insulin period?

In the decade before the discovery of insulin, the prominent American physicians Frederick Allen and Elliott Joslin advocated severe fasting and undernutrition to prolong the lives of diabetic patients. Detractors called this "starvation dieting," and some patients did indeed starve to dea...

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Detalles Bibliográficos
Autor principal: Mazur, Allan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062586/
https://www.ncbi.nlm.nih.gov/pubmed/21396115
http://dx.doi.org/10.1186/1475-2891-10-23
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author Mazur, Allan
author_facet Mazur, Allan
author_sort Mazur, Allan
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description In the decade before the discovery of insulin, the prominent American physicians Frederick Allen and Elliott Joslin advocated severe fasting and undernutrition to prolong the lives of diabetic patients. Detractors called this "starvation dieting," and some patients did indeed starve to death. Allen and Joslin promoted the therapy as a desperate application of animal experimentation to clinical treatment, and texts still describe it that way. This justification was exaggerated. The public record contains only the briefest account of relevant animal experiments, and clinical experience at the time provided little indication that severe undernutrition had better outcomes than low carbohydrate diets then in use.
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spelling pubmed-30625862011-03-23 Why were "starvation diets" promoted for diabetes in the pre-insulin period? Mazur, Allan Nutr J Review In the decade before the discovery of insulin, the prominent American physicians Frederick Allen and Elliott Joslin advocated severe fasting and undernutrition to prolong the lives of diabetic patients. Detractors called this "starvation dieting," and some patients did indeed starve to death. Allen and Joslin promoted the therapy as a desperate application of animal experimentation to clinical treatment, and texts still describe it that way. This justification was exaggerated. The public record contains only the briefest account of relevant animal experiments, and clinical experience at the time provided little indication that severe undernutrition had better outcomes than low carbohydrate diets then in use. BioMed Central 2011-03-11 /pmc/articles/PMC3062586/ /pubmed/21396115 http://dx.doi.org/10.1186/1475-2891-10-23 Text en Copyright ©2011 Mazur; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Mazur, Allan
Why were "starvation diets" promoted for diabetes in the pre-insulin period?
title Why were "starvation diets" promoted for diabetes in the pre-insulin period?
title_full Why were "starvation diets" promoted for diabetes in the pre-insulin period?
title_fullStr Why were "starvation diets" promoted for diabetes in the pre-insulin period?
title_full_unstemmed Why were "starvation diets" promoted for diabetes in the pre-insulin period?
title_short Why were "starvation diets" promoted for diabetes in the pre-insulin period?
title_sort why were "starvation diets" promoted for diabetes in the pre-insulin period?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062586/
https://www.ncbi.nlm.nih.gov/pubmed/21396115
http://dx.doi.org/10.1186/1475-2891-10-23
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