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Control of CD8αα intestinal intraepithelial lymphocyte development by TGF-β
The molecular mechanisms directing the development of TCRαβ(+)CD8αα(+) intestinal intraepithelial lymphocytes (IEL) are not thoroughly understood. Here we show that transforming growth factor-β (TGF-β) controls the development of TCRαβ(+)CD8αα(+) IEL. Mice with either a TGF-β1 null mutation or a T c...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062738/ https://www.ncbi.nlm.nih.gov/pubmed/21297643 http://dx.doi.org/10.1038/ni.1997 |