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Structure−Activity Analysis of Diffusible Lipid Electrophiles Associated with Phospholipid Peroxidation: 4-Hydroxynonenal and 4-Oxononenal Analogues

[Image: see text] Electrophile-mediated disruption of cell signal-ing is involved in the pathogenesis of several diseases including atherosclerosis and cancer. Diffusible and membrane bound lipid electrophiles are known to modify DNA and protein substrates and modulate cellular pathways including ER...

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Detalles Bibliográficos
Autores principales:	McGrath, Colleen E., Tallman, Keri A., Porter, Ned A., Marnett, Lawrence J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2011
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062932/ https://www.ncbi.nlm.nih.gov/pubmed/21291287 http://dx.doi.org/10.1021/tx100323m

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