Approaches towards the synthesis of 5-aminopyrazoles

The biological and medicinal properties of 5-aminopyrazoles have prompted enormous research aimed at developing synthetic routes to these heterocyles. This review focuses on the biological properties associated with this system. Various synthetic methods developed up to 2010 for these compounds are...

Descripción completa

Detalles Bibliográficos
Autores principales: Aggarwal, Ranjana, Kumar, Vinod, Kumar, Rajiv, Singh, Shiv P
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063075/
https://www.ncbi.nlm.nih.gov/pubmed/21448263
http://dx.doi.org/10.3762/bjoc.7.25
_version_ 1782200759401578496
author Aggarwal, Ranjana
Kumar, Vinod
Kumar, Rajiv
Singh, Shiv P
author_facet Aggarwal, Ranjana
Kumar, Vinod
Kumar, Rajiv
Singh, Shiv P
author_sort Aggarwal, Ranjana
collection PubMed
description The biological and medicinal properties of 5-aminopyrazoles have prompted enormous research aimed at developing synthetic routes to these heterocyles. This review focuses on the biological properties associated with this system. Various synthetic methods developed up to 2010 for these compounds are described, particularly those that involve the reactions of β-ketonitriles, malononitrile, alkylidenemalononitriles and their derivatives with hydrazines, as well as some novel miscellaneous methods.
format Text
id pubmed-3063075
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-30630752011-03-28 Approaches towards the synthesis of 5-aminopyrazoles Aggarwal, Ranjana Kumar, Vinod Kumar, Rajiv Singh, Shiv P Beilstein J Org Chem Review The biological and medicinal properties of 5-aminopyrazoles have prompted enormous research aimed at developing synthetic routes to these heterocyles. This review focuses on the biological properties associated with this system. Various synthetic methods developed up to 2010 for these compounds are described, particularly those that involve the reactions of β-ketonitriles, malononitrile, alkylidenemalononitriles and their derivatives with hydrazines, as well as some novel miscellaneous methods. Beilstein-Institut 2011-02-09 /pmc/articles/PMC3063075/ /pubmed/21448263 http://dx.doi.org/10.3762/bjoc.7.25 Text en Copyright © 2011, Aggarwal et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Review
Aggarwal, Ranjana
Kumar, Vinod
Kumar, Rajiv
Singh, Shiv P
Approaches towards the synthesis of 5-aminopyrazoles
title Approaches towards the synthesis of 5-aminopyrazoles
title_full Approaches towards the synthesis of 5-aminopyrazoles
title_fullStr Approaches towards the synthesis of 5-aminopyrazoles
title_full_unstemmed Approaches towards the synthesis of 5-aminopyrazoles
title_short Approaches towards the synthesis of 5-aminopyrazoles
title_sort approaches towards the synthesis of 5-aminopyrazoles
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063075/
https://www.ncbi.nlm.nih.gov/pubmed/21448263
http://dx.doi.org/10.3762/bjoc.7.25
work_keys_str_mv AT aggarwalranjana approachestowardsthesynthesisof5aminopyrazoles
AT kumarvinod approachestowardsthesynthesisof5aminopyrazoles
AT kumarrajiv approachestowardsthesynthesisof5aminopyrazoles
AT singhshivp approachestowardsthesynthesisof5aminopyrazoles

Ejemplares similares