Cargando…
Phosphatidylserine is a critical modulator for Akt activation
Akt activation relies on the binding of Akt to phosphatidylinositol-3,4,5-trisphosphate (PIP(3)) in the membrane. Here, we demonstrate that Akt activation requires not only PIP(3) but also membrane phosphatidylserine (PS). The extent of insulin-like growth factor–induced Akt activation and downstrea...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063130/ https://www.ncbi.nlm.nih.gov/pubmed/21402788 http://dx.doi.org/10.1083/jcb.201005100 |