The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets

Lipins are phosphatidate phosphatases that generate diacylglycerol (DAG). In this study, we report that yeast lipin, Pah1p, controls the formation of cytosolic lipid droplets. Disruption of PAH1 resulted in a 63% decrease in droplet number, although total neutral lipid levels did not change. This wa...

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Detalles Bibliográficos
Autores principales: Adeyo, Oludotun, Horn, Patrick J., Lee, SungKyung, Binns, Derk D., Chandrahas, Anita, Chapman, Kent D., Goodman, Joel M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063132/
https://www.ncbi.nlm.nih.gov/pubmed/21422231
http://dx.doi.org/10.1083/jcb.201010111

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