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A vertebrate N-end rule degron reveals that Orc6 is required in mitosis for daughter cell abscission

Orc6, an evolutionarily conserved component of the origin recognition complex, is essential for deoxyribonucleic acid (DNA) replication initiation from yeast to humans. Whether vertebrate Orc6 has a mitotic function remains unresolved. In vertebrates, but not yeast, its depletion causes centrosome a...

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Detalles Bibliográficos
Autores principales:	Bernal, Juan A., Venkitaraman, Ashok R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063140/ https://www.ncbi.nlm.nih.gov/pubmed/21422227 http://dx.doi.org/10.1083/jcb.201008125

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