siRNA Screening of a Targeted Library of DNA Repair Factors in HIV Infection Reveals a Role for Base Excision Repair in HIV Integration

Host DNA repair enzymes have long been assumed to play a role in HIV replication, and many different DNA repair factors have been associated with HIV. In order to identify DNA repair pathways required for HIV infection, we conducted a targeted siRNA screen using 232 siRNA pools for genes associated...

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Detalles Bibliográficos
Autores principales: Espeseth, Amy S., Fishel, Rick, Hazuda, Daria, Huang, Qian, Xu, Min, Yoder, Kristine, Zhou, Honglin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063162/
https://www.ncbi.nlm.nih.gov/pubmed/21448273
http://dx.doi.org/10.1371/journal.pone.0017612

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