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MISC-1/OGC Links Mitochondrial Metabolism, Apoptosis and Insulin Secretion
We identified MISC-1 (Mitochondrial Solute Carrier) as the C. elegans orthologue of mammalian OGC (2-oxoglutarate carrier). OGC was originally identified for its ability to transfer α-ketoglutarate across the inner mitochondrial membrane. However, we found that MISC-1 and OGC are not solely involved...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063170/ https://www.ncbi.nlm.nih.gov/pubmed/21448454 http://dx.doi.org/10.1371/journal.pone.0017827 |