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Development of Novel Zn(2+) Loaded Nanoparticles Designed for Cell-Type Targeted Drug Release in CNS Neurons: In Vitro Evidences
Intact synaptic function and plasticity are fundamental prerequisites to a healthy brain. Therefore, synaptic proteins are one of the major targets for drugs used as neuro-chemical therapeutics. Unfortunately, the majority of drugs is not able to cross the blood–brain barrier (BBB) and is therefore...
Autores principales: | Grabrucker, Andreas M., Garner, Craig C., Boeckers, Tobias M., Bondioli, Lucia, Ruozi, Barbara, Forni, Flavio, Vandelli, Maria Angela, Tosi, Giovanni |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063171/ https://www.ncbi.nlm.nih.gov/pubmed/21448455 http://dx.doi.org/10.1371/journal.pone.0017851 |
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