Expression of DDX3 Is Directly Modulated by Hypoxia Inducible Factor-1 Alpha in Breast Epithelial Cells

DEAD box protein, DDX3, is aberrantly expressed in breast cancer cells ranging from weakly invasive to aggressive phenotypes and functions as an important regulator of cancer cell growth and survival. Here, we demonstrate that hypoxia inducible factor-1α is a transcriptional activator of DDX3 in bre...

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Detalles Bibliográficos
Autores principales: Botlagunta, Mahendran, Krishnamachary, Balaji, Vesuna, Farhad, Winnard, Paul T., Bol, Guus M., Patel, Arvind H., Raman, Venu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063174/
https://www.ncbi.nlm.nih.gov/pubmed/21448281
http://dx.doi.org/10.1371/journal.pone.0017563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063174/
https://www.ncbi.nlm.nih.gov/pubmed/21448281
http://dx.doi.org/10.1371/journal.pone.0017563

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