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Testicular tuberculosis presenting with metastatic intracranial tuberculomas only: a case report

INTRODUCTION: Intracranial tuberculomas are a rare complication of tuberculosis occurring through hematogenous spread from an extracranial source, most often of pulmonary origin. Testicular tuberculosis with only intracranial spread is an even rarer finding and to the best of our knowledge, has not...

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Autores principales: Ogbole, Godwin I, Bassey, Oku S, Okolo, Clement A, Ukperi, Samson O, Ogunseyinde, Ayotunde O
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063237/
https://www.ncbi.nlm.nih.gov/pubmed/21396127
http://dx.doi.org/10.1186/1752-1947-5-100
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author Ogbole, Godwin I
Bassey, Oku S
Okolo, Clement A
Ukperi, Samson O
Ogunseyinde, Ayotunde O
author_facet Ogbole, Godwin I
Bassey, Oku S
Okolo, Clement A
Ukperi, Samson O
Ogunseyinde, Ayotunde O
author_sort Ogbole, Godwin I
collection PubMed
description INTRODUCTION: Intracranial tuberculomas are a rare complication of tuberculosis occurring through hematogenous spread from an extracranial source, most often of pulmonary origin. Testicular tuberculosis with only intracranial spread is an even rarer finding and to the best of our knowledge, has not been reported in the literature. Clinical suspicion or recognition and prompt diagnosis are important because early treatment can prevent patient deterioration and lead to clinical improvement. CASE PRESENTATION: We present the case of a 51-year-old African man with testicular tuberculosis and multiple intracranial tuberculomas who was initially managed for testicular cancer with intracranial metastasis. He had undergone left radical orchidectomy, but subsequently developed hemiparesis and lost consciousness. Following histopathological confirmation of the postoperative sample as chronic granulomatous infection due to tuberculosis, he sustained significant clinical improvement with antituberculous therapy, recovered fully and was discharged at two weeks post-treatment. CONCLUSION: The clinical presentation of intracranial tuberculomas from an extracranial source is protean, and delayed diagnosis could have devastating consequences. The need to have a high index of suspicion is important, since neuroimaging features may not be pathognomonic.
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spelling pubmed-30632372011-03-24 Testicular tuberculosis presenting with metastatic intracranial tuberculomas only: a case report Ogbole, Godwin I Bassey, Oku S Okolo, Clement A Ukperi, Samson O Ogunseyinde, Ayotunde O J Med Case Reports Case Report INTRODUCTION: Intracranial tuberculomas are a rare complication of tuberculosis occurring through hematogenous spread from an extracranial source, most often of pulmonary origin. Testicular tuberculosis with only intracranial spread is an even rarer finding and to the best of our knowledge, has not been reported in the literature. Clinical suspicion or recognition and prompt diagnosis are important because early treatment can prevent patient deterioration and lead to clinical improvement. CASE PRESENTATION: We present the case of a 51-year-old African man with testicular tuberculosis and multiple intracranial tuberculomas who was initially managed for testicular cancer with intracranial metastasis. He had undergone left radical orchidectomy, but subsequently developed hemiparesis and lost consciousness. Following histopathological confirmation of the postoperative sample as chronic granulomatous infection due to tuberculosis, he sustained significant clinical improvement with antituberculous therapy, recovered fully and was discharged at two weeks post-treatment. CONCLUSION: The clinical presentation of intracranial tuberculomas from an extracranial source is protean, and delayed diagnosis could have devastating consequences. The need to have a high index of suspicion is important, since neuroimaging features may not be pathognomonic. BioMed Central 2011-03-13 /pmc/articles/PMC3063237/ /pubmed/21396127 http://dx.doi.org/10.1186/1752-1947-5-100 Text en Copyright ©2011 Ogbole et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ogbole, Godwin I
Bassey, Oku S
Okolo, Clement A
Ukperi, Samson O
Ogunseyinde, Ayotunde O
Testicular tuberculosis presenting with metastatic intracranial tuberculomas only: a case report
title Testicular tuberculosis presenting with metastatic intracranial tuberculomas only: a case report
title_full Testicular tuberculosis presenting with metastatic intracranial tuberculomas only: a case report
title_fullStr Testicular tuberculosis presenting with metastatic intracranial tuberculomas only: a case report
title_full_unstemmed Testicular tuberculosis presenting with metastatic intracranial tuberculomas only: a case report
title_short Testicular tuberculosis presenting with metastatic intracranial tuberculomas only: a case report
title_sort testicular tuberculosis presenting with metastatic intracranial tuberculomas only: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063237/
https://www.ncbi.nlm.nih.gov/pubmed/21396127
http://dx.doi.org/10.1186/1752-1947-5-100
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