The Functions of Auxilin and Rab11 in Drosophila Suggest That the Fundamental Role of Ligand Endocytosis in Notch Signaling Cells Is Not Recycling

Notch signaling requires ligand internalization by the signal sending cells. Two endocytic proteins, epsin and auxilin, are essential for ligand internalization and signaling. Epsin promotes clathrin-coated vesicle formation, and auxilin uncoats clathrin from newly internalized vesicles. Two hypothe...

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Detalles Bibliográficos
Autores principales: Banks, Susan M. L., Cho, Bomsoo, Eun, Suk Ho, Lee, Ji-Hoon, Windler, Sarah L., Xie, Xuanhua, Bilder, David, Fischer, Janice A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063240/
https://www.ncbi.nlm.nih.gov/pubmed/21448287
http://dx.doi.org/10.1371/journal.pone.0018259

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