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Human CD14(dim) Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

Monocytes are effectors of the inflammatory response to microbes. Human CD14(+) monocytes specialize in phagocytosis and production of reactive oxygen species and secrete inflammatory cytokines in response to a broad range of microbial cues. Here, we have characterized the functions of human monocyt...

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Detalles Bibliográficos
Autores principales:	Cros, Jérôme, Cagnard, Nicolas, Woollard, Kevin, Patey, Natacha, Zhang, Shen-Ying, Senechal, Brigitte, Puel, Anne, Biswas, Subhra K., Moshous, Despina, Picard, Capucine, Jais, Jean-Philippe, D'Cruz, David, Casanova, Jean-Laurent, Trouillet, Céline, Geissmann, Fréderic
Formato:	Texto
Lenguaje:	English
Publicado:	Cell Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063338/ https://www.ncbi.nlm.nih.gov/pubmed/20832340 http://dx.doi.org/10.1016/j.immuni.2010.08.012

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