Telmisartan improves nonalcoholic steatohepatitis in medaka (Oryzias latipes) by reducing macrophage infiltration and fat accumulation

We investigated the efficacy of the antihypertensive drug telmisartan (Tel) and the mechanisms underlying the progression from simple steatosis to nonalcoholic steatohepatitis (NASH) in a medaka (Oryzias latipes) NASH model. We used the NASH activity score (NAS) developed in humans to assess the his...

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Detalles Bibliográficos
Autores principales: Kuwashiro, Shinya, Terai, Shuji, Oishi, Toshiyuki, Fujisawa, Koichi, Matsumoto, Toshihiko, Nishina, Hiroshi, Sakaida, Isao
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063342/
https://www.ncbi.nlm.nih.gov/pubmed/21327395
http://dx.doi.org/10.1007/s00441-011-1132-7

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