Micro-RNA Expression and Function in Lymphomas

The recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. Study of miRNA expression and function in animal models and human lymphomas has improve...

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Detalles Bibliográficos
Autores principales: Sandhu, Sukhinder K., Croce, Carlo M., Garzon, Ramiro
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063410/
https://www.ncbi.nlm.nih.gov/pubmed/21461378
http://dx.doi.org/10.1155/2011/347137
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author Sandhu, Sukhinder K.
Croce, Carlo M.
Garzon, Ramiro
author_facet Sandhu, Sukhinder K.
Croce, Carlo M.
Garzon, Ramiro
author_sort Sandhu, Sukhinder K.
collection PubMed
description The recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. Study of miRNA expression and function in animal models and human lymphomas has improved our knowledge of the pathogenesis of this heterogeneous disease. In this paper, we attempt to describe the expression of miRNAs and their function in lymphomas and discuss potential miRNA-based therapies in the diagnosis and treatment of lymphomas.
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spelling pubmed-30634102011-03-31 Micro-RNA Expression and Function in Lymphomas Sandhu, Sukhinder K. Croce, Carlo M. Garzon, Ramiro Adv Hematol Review Article The recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. Study of miRNA expression and function in animal models and human lymphomas has improved our knowledge of the pathogenesis of this heterogeneous disease. In this paper, we attempt to describe the expression of miRNAs and their function in lymphomas and discuss potential miRNA-based therapies in the diagnosis and treatment of lymphomas. Hindawi Publishing Corporation 2011 2011-03-22 /pmc/articles/PMC3063410/ /pubmed/21461378 http://dx.doi.org/10.1155/2011/347137 Text en Copyright © 2011 Sukhinder K. Sandhu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sandhu, Sukhinder K.
Croce, Carlo M.
Garzon, Ramiro
Micro-RNA Expression and Function in Lymphomas
title Micro-RNA Expression and Function in Lymphomas
title_full Micro-RNA Expression and Function in Lymphomas
title_fullStr Micro-RNA Expression and Function in Lymphomas
title_full_unstemmed Micro-RNA Expression and Function in Lymphomas
title_short Micro-RNA Expression and Function in Lymphomas
title_sort micro-rna expression and function in lymphomas
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063410/
https://www.ncbi.nlm.nih.gov/pubmed/21461378
http://dx.doi.org/10.1155/2011/347137
work_keys_str_mv AT sandhusukhinderk micrornaexpressionandfunctioninlymphomas
AT crocecarlom micrornaexpressionandfunctioninlymphomas
AT garzonramiro micrornaexpressionandfunctioninlymphomas

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