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Molecular Mechanism of Cyclodextrin Mediated Cholesterol Extraction

The depletion of cholesterol from membranes, mediated by β-cyclodextrin (β-CD) is well known and documented, but the molecular details of this process are largely unknown. Using molecular dynamics simulations, we have been able to study the CD mediated extraction of cholesterol from model membranes,...

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Detalles Bibliográficos
Autores principales: López, Cesar A., de Vries, Alex H., Marrink, Siewert J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063748/
https://www.ncbi.nlm.nih.gov/pubmed/21455285
http://dx.doi.org/10.1371/journal.pcbi.1002020