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Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans
Zinc is an essential trace element involved in a wide range of biological processes and human diseases. Zinc excess is deleterious, and animals require mechanisms to protect against zinc toxicity. To identify genes that modulate zinc tolerance, we performed a forward genetic screen for Caenorhabditi...
Autores principales: | Murphy, John T., Bruinsma, Janelle J., Schneider, Daniel L., Collier, Sara, Guthrie, James, Chinwalla, Asif, Robertson, J. David, Mardis, Elaine R., Kornfeld, Kerry |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063764/ https://www.ncbi.nlm.nih.gov/pubmed/21455490 http://dx.doi.org/10.1371/journal.pgen.1002013 |
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