MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

Increased motility and invasiveness of pancreatic cancer cells are associated with epithelial to mesenchymal transition (EMT). Snai1 and Slug are zinc-finger transcription factors that trigger this process by repressing E-cadherin and enhancing vimentin and N-Cadherin protein expression. However, th...

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Detalles Bibliográficos
Autores principales: Roy, Lopamudra Das, Sahraei, Mahnaz, Subramani, Durai B., Besmer, Dahlia, Nath, Sritama, Tinder, Teresa L., Bajaj, Ekta, Shanmugam, Kandavel, Lee, Yong Yook, Hwang, Sun IL, Gendler, Sandra J., Mukherjee, Pinku
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063863/
https://www.ncbi.nlm.nih.gov/pubmed/21102519
http://dx.doi.org/10.1038/onc.2010.526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063863/
https://www.ncbi.nlm.nih.gov/pubmed/21102519
http://dx.doi.org/10.1038/onc.2010.526

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