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MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
Increased motility and invasiveness of pancreatic cancer cells are associated with epithelial to mesenchymal transition (EMT). Snai1 and Slug are zinc-finger transcription factors that trigger this process by repressing E-cadherin and enhancing vimentin and N-Cadherin protein expression. However, th...
Autores principales: | Roy, Lopamudra Das, Sahraei, Mahnaz, Subramani, Durai B., Besmer, Dahlia, Nath, Sritama, Tinder, Teresa L., Bajaj, Ekta, Shanmugam, Kandavel, Lee, Yong Yook, Hwang, Sun IL, Gendler, Sandra J., Mukherjee, Pinku |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063863/ https://www.ncbi.nlm.nih.gov/pubmed/21102519 http://dx.doi.org/10.1038/onc.2010.526 |
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