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Systematic Evaluation of the Descriptive and Predictive Performance of Paediatric Morphine Population Models

PURPOSE: A framework for the evaluation of paediatric population models is proposed and applied to two different paediatric population pharmacokinetic models for morphine. One covariate model was based on a systematic covariate analysis, the other on fixed allometric scaling principles. METHODS: The...

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Detalles Bibliográficos
Autores principales:	Krekels, Elke H. J., van Hasselt, Johan G. C., Tibboel, Dick, Danhof, Meindert, Knibbe, Catherijne A. J.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer US 2010
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063866/ https://www.ncbi.nlm.nih.gov/pubmed/21153913 http://dx.doi.org/10.1007/s11095-010-0333-1

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