Cargando…

Myopenia—a new universal term for muscle wasting

A universal term describing the presence of clinically relevant muscle wasting that warrants medical intervention is required. The term sarcopenia might be used in this context. However, common use now means that sarcopenia is more often regarded as synonymous with age-associated muscle wasting in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Fearon, Kenneth, Evans, William J., Anker, Stefan D.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063883/
https://www.ncbi.nlm.nih.gov/pubmed/21475620
http://dx.doi.org/10.1007/s13539-011-0025-7
_version_ 1782200850528075776
author Fearon, Kenneth
Evans, William J.
Anker, Stefan D.
author_facet Fearon, Kenneth
Evans, William J.
Anker, Stefan D.
author_sort Fearon, Kenneth
collection PubMed
description A universal term describing the presence of clinically relevant muscle wasting that warrants medical intervention is required. The term sarcopenia might be used in this context. However, common use now means that sarcopenia is more often regarded as synonymous with age-associated muscle wasting in the elderly. We suggest the term “myopenia” to indicate the presence of clinically relevant muscle wasting due to any illness and at any age. This term would translate well into any language and is sufficiently specific if appropriately defined. We suggest to define myopenia as a clinically relevant degree of muscle wasting that is associated either with impaired functional capacity and/or with increased risk of morbidity or mortality. The precise cut-points to define myopenia may be different in various diseases. Myopenia could be diagnosed when a certain degree of muscle wasting over time has occurred (for instance, at least 5% in 6–12 months) or when muscle mass is below a certain threshold level (for instance, the <5th centile of healthy 30-year-olds or a fat-free mass index <16 kg/m(2) for men and <15 kg/m(2) for women). Future studies need to refine these in a disease-specific manner and link them to degrees of functional impairment that are clinically relevant and/or to degrees of risk of morbid or fatal events.
format Text
id pubmed-3063883
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-30638832011-04-05 Myopenia—a new universal term for muscle wasting Fearon, Kenneth Evans, William J. Anker, Stefan D. J Cachexia Sarcopenia Muscle Editorial A universal term describing the presence of clinically relevant muscle wasting that warrants medical intervention is required. The term sarcopenia might be used in this context. However, common use now means that sarcopenia is more often regarded as synonymous with age-associated muscle wasting in the elderly. We suggest the term “myopenia” to indicate the presence of clinically relevant muscle wasting due to any illness and at any age. This term would translate well into any language and is sufficiently specific if appropriately defined. We suggest to define myopenia as a clinically relevant degree of muscle wasting that is associated either with impaired functional capacity and/or with increased risk of morbidity or mortality. The precise cut-points to define myopenia may be different in various diseases. Myopenia could be diagnosed when a certain degree of muscle wasting over time has occurred (for instance, at least 5% in 6–12 months) or when muscle mass is below a certain threshold level (for instance, the <5th centile of healthy 30-year-olds or a fat-free mass index <16 kg/m(2) for men and <15 kg/m(2) for women). Future studies need to refine these in a disease-specific manner and link them to degrees of functional impairment that are clinically relevant and/or to degrees of risk of morbid or fatal events. Springer-Verlag 2011-03-25 2011-03 /pmc/articles/PMC3063883/ /pubmed/21475620 http://dx.doi.org/10.1007/s13539-011-0025-7 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Editorial
Fearon, Kenneth
Evans, William J.
Anker, Stefan D.
Myopenia—a new universal term for muscle wasting
title Myopenia—a new universal term for muscle wasting
title_full Myopenia—a new universal term for muscle wasting
title_fullStr Myopenia—a new universal term for muscle wasting
title_full_unstemmed Myopenia—a new universal term for muscle wasting
title_short Myopenia—a new universal term for muscle wasting
title_sort myopenia—a new universal term for muscle wasting
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063883/
https://www.ncbi.nlm.nih.gov/pubmed/21475620
http://dx.doi.org/10.1007/s13539-011-0025-7
work_keys_str_mv AT fearonkenneth myopeniaanewuniversaltermformusclewasting
AT evanswilliamj myopeniaanewuniversaltermformusclewasting
AT ankerstefand myopeniaanewuniversaltermformusclewasting