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A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel

Paragonimiasis is an infectious disease caused by trematodes of the genus Paragonimus. This trematode can be treated successfully with praziquantel in more than 90% of the cases. Although praziquantel is generally well tolerated, anaphylactic reactions to this drug have been reported in a few cases....

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Detalles Bibliográficos
Autores principales: Kyung, Sun Young, Cho, Yong Kyun, Kim, Yu Jin, Park, Jeong-Woong, Jeong, Sung Hwan, Lee, Jae-Ik, Sung, Yon Mi, Lee, Sang Pyo
Formato: Texto
Lenguaje:English
Publicado: The Korean Society for Parasitology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063930/
https://www.ncbi.nlm.nih.gov/pubmed/21461273
http://dx.doi.org/10.3347/kjp.2011.49.1.73
Descripción
Sumario:Paragonimiasis is an infectious disease caused by trematodes of the genus Paragonimus. This trematode can be treated successfully with praziquantel in more than 90% of the cases. Although praziquantel is generally well tolerated, anaphylactic reactions to this drug have been reported in a few cases. We report here a 46-year-old Korean female with paragonimiasis, presumed to be due to Paragonimus westermani, who displayed an allergic reaction to praziquantel and resistance to triclabendazole treatment. The patient was successfully treated with praziquantel following a rapid desensitization procedure. Desensitization to praziquantel could be considered when no alternative drugs are available.