A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel

Paragonimiasis is an infectious disease caused by trematodes of the genus Paragonimus. This trematode can be treated successfully with praziquantel in more than 90% of the cases. Although praziquantel is generally well tolerated, anaphylactic reactions to this drug have been reported in a few cases....

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Autores principales: Kyung, Sun Young, Cho, Yong Kyun, Kim, Yu Jin, Park, Jeong-Woong, Jeong, Sung Hwan, Lee, Jae-Ik, Sung, Yon Mi, Lee, Sang Pyo
Formato: Texto
Lenguaje:English
Publicado: The Korean Society for Parasitology 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063930/
https://www.ncbi.nlm.nih.gov/pubmed/21461273
http://dx.doi.org/10.3347/kjp.2011.49.1.73
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author Kyung, Sun Young
Cho, Yong Kyun
Kim, Yu Jin
Park, Jeong-Woong
Jeong, Sung Hwan
Lee, Jae-Ik
Sung, Yon Mi
Lee, Sang Pyo
author_facet Kyung, Sun Young
Cho, Yong Kyun
Kim, Yu Jin
Park, Jeong-Woong
Jeong, Sung Hwan
Lee, Jae-Ik
Sung, Yon Mi
Lee, Sang Pyo
author_sort Kyung, Sun Young
collection PubMed
description Paragonimiasis is an infectious disease caused by trematodes of the genus Paragonimus. This trematode can be treated successfully with praziquantel in more than 90% of the cases. Although praziquantel is generally well tolerated, anaphylactic reactions to this drug have been reported in a few cases. We report here a 46-year-old Korean female with paragonimiasis, presumed to be due to Paragonimus westermani, who displayed an allergic reaction to praziquantel and resistance to triclabendazole treatment. The patient was successfully treated with praziquantel following a rapid desensitization procedure. Desensitization to praziquantel could be considered when no alternative drugs are available.
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spelling pubmed-30639302011-03-31 A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel Kyung, Sun Young Cho, Yong Kyun Kim, Yu Jin Park, Jeong-Woong Jeong, Sung Hwan Lee, Jae-Ik Sung, Yon Mi Lee, Sang Pyo Korean J Parasitol Case Report Paragonimiasis is an infectious disease caused by trematodes of the genus Paragonimus. This trematode can be treated successfully with praziquantel in more than 90% of the cases. Although praziquantel is generally well tolerated, anaphylactic reactions to this drug have been reported in a few cases. We report here a 46-year-old Korean female with paragonimiasis, presumed to be due to Paragonimus westermani, who displayed an allergic reaction to praziquantel and resistance to triclabendazole treatment. The patient was successfully treated with praziquantel following a rapid desensitization procedure. Desensitization to praziquantel could be considered when no alternative drugs are available. The Korean Society for Parasitology 2011-03 2011-03-18 /pmc/articles/PMC3063930/ /pubmed/21461273 http://dx.doi.org/10.3347/kjp.2011.49.1.73 Text en © 2011, Korean Society for Parasitology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kyung, Sun Young
Cho, Yong Kyun
Kim, Yu Jin
Park, Jeong-Woong
Jeong, Sung Hwan
Lee, Jae-Ik
Sung, Yon Mi
Lee, Sang Pyo
A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
title A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
title_full A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
title_fullStr A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
title_full_unstemmed A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
title_short A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
title_sort paragonimiasis patient with allergic reaction to praziquantel and resistance to triclabendazole: successful treatment after desensitization to praziquantel
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063930/
https://www.ncbi.nlm.nih.gov/pubmed/21461273
http://dx.doi.org/10.3347/kjp.2011.49.1.73
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