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Loss of Rab27 function results in abnormal lung epithelium structure in mice
Rab27 small GTPases regulate secretion and movement of lysosome-related organelles such as T cell cytolytic granules and platelet-dense granules. Previous studies indicated that Rab27a and Rab27b are expressed in the murine lung suggesting that they regulate secretory processes in the lung. Consiste...
Autores principales: | Bolasco, Giulia, Tracey-White, Dhani C., Tolmachova, Tanya, Thorley, Andrew J., Tetley, Teresa D., Seabra, Miguel C., Hume, Alistair N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063958/ https://www.ncbi.nlm.nih.gov/pubmed/21160031 http://dx.doi.org/10.1152/ajpcell.00446.2010 |
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