Hyperuricemia as a Mediator of the Proinflammatory Endocrine Imbalance in the Adipose Tissue in a Murine Model of the Metabolic Syndrome

OBJECTIVE: Hyperuricemia is strongly associated with obesity and metabolic syndrome and can predict visceral obesity and insulin resistance. Previously, we showed that soluble uric acid directly stimulated the redox-dependent proinflammatory signaling in adipocytes. In this study we demonstrate the...

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Detalles Bibliográficos
Autores principales: Baldwin, William, McRae, Steven, Marek, George, Wymer, David, Pannu, Varinderpal, Baylis, Chris, Johnson, Richard J., Sautin, Yuri Y.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064099/
https://www.ncbi.nlm.nih.gov/pubmed/21346177
http://dx.doi.org/10.2337/db10-0916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064099/
https://www.ncbi.nlm.nih.gov/pubmed/21346177
http://dx.doi.org/10.2337/db10-0916

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