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Role of Inflammation and Insulin Resistance in Endothelial Progenitor Cell Dysfunction

OBJECTIVE: Endothelial progenitor cells (EPCs) are decreased in number and function in type 2 diabetes. Mechanisms by which this dysfunction occurs are largely unknown. We tested the hypothesis that a chronic inflammatory environment leads to insulin signaling defects in EPCs and thereby reduces the...

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Detalles Bibliográficos
Autores principales: Desouza, Cyrus V., Hamel, Frederick G., Bidasee, Keshore, O’Connell, Kelly
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064102/
https://www.ncbi.nlm.nih.gov/pubmed/21346178
http://dx.doi.org/10.2337/db10-0875